解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract:BACKGROUND AND AIMS:Congenital extrahepatic portosystemic shunt (CEPS) is a rare venous malformation in which mesenteric venous blood drains directly into the systemic circulation. It is still a matter of debate whether conservative or operative strategies should be used to treat symptomatic CEPS. The aim of this study...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.035
更新日期:2012-03-01 00:00:00
abstract:BACKGROUND:Carotid endarterectomy (CEA) reduces the risk of stroke in selected patients with symptomatic and asymptomatic carotid disease, but its beneficial influence on cognitive performance in the elderly remains debatable. This prospective study sought to determine early and long-term neurocognitive outcomes after ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.06.031
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:The clinical impact of the distal pancreatectomy with en-bloc celiac axis resection for locally advanced pancreatic body cancer remains unclear. METHODS:We reviewed the records of 13 patients who underwent distal pancreatectomy-celiac axis resection between 1991 and 2009, 58 patients who underwent distal pa...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.06.030
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:High rates of extrapancreatic malignancies (EPM) have been observed in patients with intraductal papillary mucinous neoplasm (IPMN). IPMN in patients with familial pancreatic cancer have also been reported. Our purpose was to evaluate the association of IPMN with EPM, malignancies in family members, and germ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.06.036
更新日期:2012-01-01 00:00:00
abstract:BACKGROUND:Bilateral axillo-breast approach (BABA) robotic thyroidectomy (RoT) has good postoperative and excellent cosmetic outcomes. To assess the surgical completeness of BABA RoT, it was compared to open thyroidectomy (OT) after propensity score matching of the cohorts. METHODS:Between 2008 and 2010, 760 patients ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.09.015
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:Pheochromocytoma (Pheo) is usually considered a sporadic disease. Recently, an increasing rate of genetically based tumors has been reported. However, the need for systematic screening of unsuspected germline mutations in apparently sporadic forms is still debated. This study aimed to assess the effective ra...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.09.024
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:The role of routine central lymph node dissection (CLND) for papillary thyroid cancer (PTC) remains controversial. The aim of this study was to evaluate the impact of routine CLND after total thyroidectomy (TTx) in the management of patients with PTC who were clinically node negative at presentation with emp...
journal_title:Surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.surg.2011.09.003
更新日期:2011-12-01 00:00:00
abstract:BACKGROUND:The observed to expected (O:E) mortality based on Injury Severity Scores (ISS) has been used to assess quality of trauma center (TC) care. Injuries in the elderly have increased, and these patients often have advanced directives, on occasion limiting aggressive care even for potentially survivable injuries; ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.065
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:This study was conducted to determine if team training using a federally sponsored team training program improves operating room (OR) performance and culture. METHODS:The TeamSTEPPS program, a team training program designed and tested for health care applications, was provided to the OR staff. The training ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.076
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:Outcomes of bariatric surgery in patients with a body mass index (BMI) <35 kg/m(2) have been an active area of investigation. We examined the comparative effectiveness of Roux-en-Y gastric bypass (RYGB) to routine medical management (nonsurgical controls; NSCs) in achieving appropriate targets defined by the...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.069
更新日期:2011-10-01 00:00:00
abstract:BACKGROUND:The goal of this study was to determine, in lung transplant patients, if laparoscopic antireflux surgery (LARS) is an effective means to prevent aspiration as defined by the presence of pepsin in the bronchoalveolar lavage fluid (BALF). METHODS:Between September 2009 and November 2010, we collected BALF fro...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.053
更新日期:2011-10-01 00:00:00
abstract:INTRODUCTION:Laparoscopic adrenalectomy (LA) is a safe minimally invasive approach for treatment of pheochromocytoma (PHEO). Posterior retroperitoneoscopic adrenalectomy (PRA) is an alternative minimally invasive technique; however, there is a lack of data regarding the appropriateness of this approach in patients with...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.07.004
更新日期:2011-09-01 00:00:00
abstract:BACKGROUND:Understanding predictors of mortality in bariatric surgery enables surgeons to use these factors for analysis of risk-adjusted mortality and aids in the surgical decision making and informed consent process. OBJECTIVES:To evaluate the effect of patient characteristics (age, gender, race, and payer type), pr...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.05.020
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:We report pharmacokinetic (PK) data, evaluation of modifications for increased stability, evaluation for cellular uptake, and mediation of regression of breast cancer for the aptamer OPN-R3. METHODS:The OPN-R3 aptamer was assessed for PK data in vivo with additional comparison of IV and subcutaneous dosing....
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.05.015
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:Glucagon-like peptide-2 induces small intestine mucosal epithelial cell proliferation and may have benefit for patients who suffer from short bowel syndrome. However, glucagon-like peptide-2 is inactivated rapidly in vivo by dipeptidyl peptidase IV. Therefore, we hypothesized that selectively inhibiting dipe...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.05.013
更新日期:2011-08-01 00:00:00
abstract:BACKGROUND:The proportion of positive among examined lymph nodes (lymph node ratio [LNR]) has been recently proposed as an useful and easy-to-calculate prognostic factor for patients with cutaneous melanoma. However, its independence from the standard prognostic system TNM has not been formally proven in a large series...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2011.02.021
更新日期:2011-07-01 00:00:00
abstract::The Consortium of American College of Surgeons-Accredited Education Institutes was created to explore new opportunities in simulation-based surgical education and training beyond the scope of individual accredited institutes. During the Third Annual Meeting of the Consortium of American College of Surgeons-Accredited ...
journal_title:Surgery
pub_type:
doi:10.1016/j.surg.2010.11.010
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:Our aim was to identify differential expression of genes in hepatocellular carcinoma (HCC) with the ultimate goal of discovering novel diagnostic and therapeutic targets. METHODS:We examined differences in gene expression between HCC and noncancerous liver tissue using a cDNA array with probes for 15,843 ge...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.12.007
更新日期:2011-06-01 00:00:00
abstract:BACKGROUND:The objective of this study was to examine the clinicopathologic characteristics of solid pseudopapillary tumors (SPTs) of the pancreas, including the risk factors for disease recurrence and their effects on survival. METHODS:The medical records of 114 patients who underwent surgery for a pathologically con...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.11.005
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Previous studies using simulation-based curricula have focused largely on technical skills. We developed a set of simulation-based modules that focus on intraoperative decision making. The objective of this study was to conduct a faculty evaluation of: (1) the usefulness of 4 newly developed, simulation-base...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.10.010
更新日期:2011-04-01 00:00:00
abstract:BACKGROUND:The purpose of this study was to investigate the effects of treating human thyroid cancer cell lines with demethylating agents and histone deacetylase (HDAC) inhibitors to see if they would downregulate expression and activity of the matrix metalloproteinases (MMP)-2 and MMP-9, resulting in inhibition of gro...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.10.007
更新日期:2011-04-01 00:00:00
abstract::An abdominal operation combines a somatic abdominal wall wound with a second autonomic wound to the peritoneal cavity and viscera and little attention has been paid the autonomic/peritoneal wound that communicates directly to the brain by the vagus nerve. Moreover, vagal input originating from the peritoneum modulates...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.10.020
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:To clarify the biologic behavior of the early signet-ring cell cancers (SRCs) by comparing the clinicopathologic features and the incidence of lymph node metastasis between different histologic types of early gastric cancer (EGC) and to propose the indications of endoscopic surgery for SRCs. METHODS:Clinico...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.07.006
更新日期:2011-03-01 00:00:00
abstract:BACKGROUND:Neuroendocrine neoplasms most commonly metastasize to the liver. Operative extirpation of neuroendocrine neoplasm hepatic metastases improves symptoms and seems to improve survival, but subsequent evidence is required. The current study evaluates the progression-free survival and overall survival of patients...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.06.008
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:The aims of the present study were to confirm the consumption coagulopathy of disseminated intravascular coagulation with the fibrinolytic phenotype at an early phase of trauma and to test the hypothesis that thrombin-activatable fibrinolysis inhibitor, neutrophil elastase, and plasmin contribute to the incr...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.06.010
更新日期:2011-02-01 00:00:00
abstract:BACKGROUND:The gastrointestinal mucosa is an important route of entry for microbial pathogens. The immune cells of Peyer's patch (PP) compartments contribute to the active immune response against infection. Although local anesthetics are widely used in clinical practice, it remains unclear whether local anesthetics suc...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.03.024
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Vascular complications are major complications after living donor liver transplantation (LDLT), especially in biliary atresia (BA). Early diagnosis and treatment of portal vein thrombosis (PVT) may ensure optimal graft function and good recipient survival. Our aim was to find any association between pre- and...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.04.018
更新日期:2011-01-01 00:00:00
abstract:BACKGROUND:Cytologically indeterminate thyroid nodules represent a diagnostic and therapeutic challenge. In 2007, the National Cancer Institute recommended The Bethesda System for Reporting Thyroid Cytopathology (TBSRTC) as a means of improving the accuracy of thyroid cytopathology. Our objective was to determine the e...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.09.017
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:Hypoparathyroidism is the most frequent permanent complication of thyroid surgery. Our hypothesis is that human precursor cells in culture can be differentiated into parathyroid cells and used to reconstitute function. Human embryonic stem cells (hESCs) are a stable model to study differentiation into parath...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.09.021
更新日期:2010-12-01 00:00:00
abstract:BACKGROUND:A stereotype of surgeons' personality persists in the general public and among health-care professionals. Only a few studies have attempted to describe this "surgical personality" in detail. The aim of this study was to investigate the personality traits of surgeons compared with internists and to prove the ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.03.001
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Operative therapy for Crohn's disease (CD) recurrence is supposed to be more complex and demanding than primary resection. The purpose of this study was to assess a postoperative course after reoperation for the recurrence of CD. METHODS:From 1998 to 2008, 61 patients underwent reoperation for the recurrenc...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.02.001
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Neoadjuvant chemotherapy (NACT) has been frequently used for locally advanced esophageal squamous cell cancer (ESCC). It is therefore important to establish criteria for evaluating the response to NACT based on survival analysis. METHODS:This study analyzed 100 patients with ESCC (cT1, 2/3/4:25/57/18, cN0/1...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.02.016
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Bioresorbable membranes composed of hyaluronic acid and carboxymethylcellulose (HA/CMC) are the most effective method to prevent intra-abdominal adhesions; however, their efficacy may be limited to the site of application. Previous studies in our laboratory have shown that the intraperitoneal administration ...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.01.024
更新日期:2010-11-01 00:00:00
abstract:BACKGROUND:Diaphragm pacing (DP) can replace mechanical ventilation in tetraplegics and in trials has assisted respiration in amyotrophic lateral sclerosis patients. This report describes results of DP in patients with cardiac pacemakers. METHODS:Prospective, single-center and multicenter, nonrandomized, controlled, i...
journal_title:Surgery
pub_type: 杂志文章,多中心研究
doi:10.1016/j.surg.2010.07.008
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Regional surgical quality improvement consortiums are becoming more common. Herein we have reported the effectiveness of a statewide consortium focusing on open vascular operative procedures. METHODS:The statewide Michigan Surgical Quality Consortium was established in 2005 with 16 hospitals that report cas...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.07.009
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:In clinically node-negative papillary thyroid microcarcinoma (PTMC), the frequency of subclinical lymph node metastasis (LNM) in the central cervical compartment (subclinical central LNM) has been reported to be as great as 65%. Routine prophylactic central compartment lymph node dissection (CLND) has been d...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.01.003
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:We previously developed an intraoperative 10-point Surgical Apgar Score-based on blood loss, lowest heart rate, and lowest mean arterial pressure-to predict major complications after colorectal resection. However, because complications often arise after uncomplicated hospitalizations, we sought to evaluate w...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.01.015
更新日期:2010-09-01 00:00:00
abstract:BACKGROUND:The role of routine prophylactic central-neck lymph node dissection (CLND) for papillary thyroid cancer (PTC) remains controversial. We perform CLND for PTC only in patients with enlarged nodes as determined by preoperative ultrasound and intraoperative inspection and palpation. METHODS:We identified all pa...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.03.021
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Transplantation of pancreatic islets is an effective treatment for select patients with type 1 diabetes. Improved cellular therapy results may be realized by altering the gene expression profile of transplanted islets. Current viral and nonviral vectors used to introduce nucleic acids for gene regulation hol...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.05.013
更新日期:2010-08-01 00:00:00
abstract:BACKGROUND:Cigarette smoke and nicotine are among the leading environmental risk factors for developing pancreatic ductal adenocarcinoma (PDA). We showed recently that nicotine induces osteopontin (OPN), a protein that plays critical roles in inflammation and tumor metastasis. We identified an OPN isoform, OPNc, that i...
journal_title:Surgery
pub_type: 杂志文章
doi:10.1016/j.surg.2010.05.002
更新日期:2010-08-01 00:00:00